An array of regulatory proteins have been found , which inhibit the formation of central enzymes involved in early stages of the complement activation pathway . these include membrane cofactor protein ( mcp cd46 ) , decay - accelerating factor protein ( daf cd5 5 ) , complement receptor 1 ( cr1 , cd35 ) , as well as cd59 , which inhibits formation of the membrane attack complex during later stages . these regulatory factors are widely expressed and abundant on many cells , and in fluids of reproductive system 目前發(fā)現,機體多種細胞以及生殖系統(tǒng)的體液中表達和分泌豐富的補體調控蛋白,包括作用于補體活化早期階段的cd55 、 cd46 、 cd35和作用于補體活化終末階段的cd59 ,它們分別通過抑制補體活化過程中關鍵的c3 、 c5轉化酶和抑制形成膜攻擊單位,抵抗補體對自身組織細胞的攻擊。
百科解釋
Erythrocyte complement receptor 1 (CR1, also known as CD35, C3b/C4b receptor and immune adherence receptor) is a human gene.